黄伟 副教授

.Zhuo, L. S.;# Wang, M. S.;# Wu, X. F.;# Xu, H. C.;# Gong, Y.; Yu, Z. C.; Tian, Y. G.; Pang, C.; Hao, G. F.; Huang, W.;* Yang, G. F.* Discovery of Next-Generation Tropomyosin Receptor Kinase (TRK) Inhibitors for Combatting Multiple Resistance Associated with Protein Mutation. J. Med. Chem. 2021, 64, 15503-15514. (IF2020 = 7.446，一区)

.Wang, M. S.;# Gong, Y.;# Yu, Z. C.; Tian, Y. G.; Zhuo, L. S.;* Huang, W.*; She, N. F.* Grignard Reagent Utilization Enables a Practical and Scalable Construction of 3-Substituted 5-chloro-1,6-naphthyridin-4-one Derivatives. Molecules. 2020, 25, 5667. (IF2020 = 4.411)

.Zhuo, L. S.;# Wu, X. F.;# Wang, M. S.; # Xu, H. C.; Yang, F. P.; Tian, Y. G.; Zhao, X. E.; Ming, Z. H.; Zhu, X. L.; Hao, G. F.;* Huang, W.* Structure–activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy. Eur. J. Med. Chem. 2020, 208, 112785. (IF2020 = 6.514，一区)

.Wang, M. S.;# Xu, H. C.;# Gong, Y.;# Qu, R. Y.; Zhuo, L. S.;* Huang, W.* Efficient Arylation of 2,7-Naphthyridin-1(2H)‑one with Diaryliodonium Salts and Discovery of a New Selective MET/AXL Kinase Inhibitor. ACS. Comb. Sci. 2020, 22, 457-467. (IF2020 = 3.784，二区)

Yang, G. F.; Huang, W.; Zhuo, L. S.; Xu, H. C.; Wang, M. S. Pyrazolopyrimidine Compounds, Pharmaceutical Composition and Application thereof. 03/19/2020, PCT International Patent. WO2020187291A1;

Yang, G. F.; Huang, W.; Zhuo, L. S.; Xu, H. C.; Wang, M. S. Pyrazolopyrimidine Compounds, Pharmaceutical Composition and Application thereof. 09/17/2021, US Patent. US17440362;

Yang, G. F.; Huang, W.; Zhuo, L. S.; Xu, H. C.; Wang, M. S. Pyrazolopyrimidine Compounds, Pharmaceutical Composition and Application thereof. 10/01/2021, European Patent. EP20774324.6;

Yang, G. F.; Huang, W.; Zhuo, L. S.; Xu, H. C.; Wang, M. S. Pyrazolopyrimidine Compounds, Pharmaceutical Composition and Application thereof. 09/17/2021, Japanese Patent. JP52101996115;